Kokkinos et al: The influence of age at total hip replacement on perioperative complications in dogs
Veterinary Surgery 3, 2025

🔍 Key Findings

  • Study population: 116 dogs underwent cementless THR; grouped by age:
    • Group A: ≤6 months (n = 27)
    • Group B: >6 to ≤12 months (n = 41)
    • Group C: >12 months (n = 48)
  • Overall perioperative complication rate: 31.9% (37/116)
    • Group A: 22.2%
    • Group B: 26.8%
    • Group C: 41.7%
  • No significant difference in total complication rate by age (p = .207), though older dogs (Group C) had numerically higher rates.
  • Luxation was significantly more common in dogs >12 months:
    • Group C: 14.6% vs. Group A (0%) and Group B (2.4%) → p = .049
  • Most common complications: luxation (9.5%) and intraoperative fissure or fracture (9.5%)
  • Time under anesthesia and surgery duration were not associated with complication risk (p = .297 and p = .781)
  • No infections or aseptic loosening observed during the 8-week follow-up.
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs
The influence of age at total hip replacement on perioperative complications in dogs

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Kokkinos et al: The influence of age at total hip replacement on perioperative complications in dogs
Veterinary Surgery 3, 2025

🔍 Key Findings

  • Study population: 116 dogs underwent cementless THR; grouped by age:
    • Group A: ≤6 months (n = 27)
    • Group B: >6 to ≤12 months (n = 41)
    • Group C: >12 months (n = 48)
  • Overall perioperative complication rate: 31.9% (37/116)
    • Group A: 22.2%
    • Group B: 26.8%
    • Group C: 41.7%
  • No significant difference in total complication rate by age (p = .207), though older dogs (Group C) had numerically higher rates.
  • Luxation was significantly more common in dogs >12 months:
    • Group C: 14.6% vs. Group A (0%) and Group B (2.4%) → p = .049
  • Most common complications: luxation (9.5%) and intraoperative fissure or fracture (9.5%)
  • Time under anesthesia and surgery duration were not associated with complication risk (p = .297 and p = .781)
  • No infections or aseptic loosening observed during the 8-week follow-up.

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Multiple Choice Questions on this study

In Kokkinos 2025 et al., on THR age effects, what was the most commonly reported perioperative complication?

A. Dislocation
B. Femoral fracture
C. Infection
D. Aseptic loosening
E. Hemorrhage

Answer: Dislocation

Explanation: Dislocation was the most frequent complication overall in the cohort.
In Kokkinos 2025 et al., on THR age effects, what age group had the highest overall complication rate following total hip replacement?

A. Dogs <6 months
B. Dogs 6–12 months
C. Dogs 12–24 months
D. Dogs >24 months
E. No difference was found

Answer: Dogs <6 months

Explanation: Younger dogs (<6 months) experienced significantly higher overall complication rates compared to older age groups.
In Kokkinos 2025 et al., on THR age effects, which perioperative complication was significantly more common in dogs <6 months of age?

A. Femoral fracture
B. Dislocation
C. Infection
D. Delayed union
E. Implant loosening

Answer: Dislocation

Explanation: Dogs <6 months had a significantly higher incidence of dislocation than dogs >24 months of age.
In Kokkinos 2025 et al., on THR age effects, which variable remained significantly associated with complications on multivariable analysis?

A. Body weight
B. Sex
C. Surgical approach
D. Age at surgery
E. Implant type

Answer: Age at surgery

Explanation: Only age <6 months was statistically associated with increased complication risk on multivariable analysis.
In Kokkinos 2025 et al., on THR age effects, what best describes the clinical recommendation based on the study findings?

A. THR is contraindicated in dogs <6 months
B. Only cemented THR should be used in juveniles
C. Early-age THR should be approached with caution
D. THR should be delayed until >2 years
E. Age had no influence on outcome

Answer: Early-age THR should be approached with caution

Explanation: Due to higher complication rates in young dogs, surgeons are advised to exercise caution in elective early-age THR.

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