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Kalmukov et al: Ex vivo evaluation of a novel cell salvage device to recover canine erythrocytes
Veterinary Surgery 8, 2022

🔍 Key Findings

  • Direct suction salvaged more red blood cell mass (rbcM) than swab washing: 88.43% vs 84.74% (p = .015)
  • Swab washing still achieved high recovery (84.74%), making it a viable adjunct when suction is not possible
  • No significant difference in post-salvage PCV between methods (~34% for Su and ~33.9% for Sw)
  • Total salvaged blood volume was significantly higher using direct suction (143 mL vs 139.8 mL; p < .001)
  • Leukocytes are removed during salvage, potentially lowering risk of cytokine-mediated transfusion reactions
  • Expired pRBCs were used, but device still achieved high RBC recovery, supporting clinical utility
  • Swab washing via manual agitation may cause more RBC destruction than direct suction
  • Cell salvage may avoid complications of allogeneic transfusions, like storage lesions and immunologic reactions

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← Articles

Kalmukov et al: Ex vivo evaluation of a novel cell salvage device to recover canine erythrocytes
Veterinary Surgery 8, 2022

🔍 Key Findings

  • Direct suction salvaged more red blood cell mass (rbcM) than swab washing: 88.43% vs 84.74% (p = .015)
  • Swab washing still achieved high recovery (84.74%), making it a viable adjunct when suction is not possible
  • No significant difference in post-salvage PCV between methods (~34% for Su and ~33.9% for Sw)
  • Total salvaged blood volume was significantly higher using direct suction (143 mL vs 139.8 mL; p < .001)
  • Leukocytes are removed during salvage, potentially lowering risk of cytokine-mediated transfusion reactions
  • Expired pRBCs were used, but device still achieved high RBC recovery, supporting clinical utility
  • Swab washing via manual agitation may cause more RBC destruction than direct suction
  • Cell salvage may avoid complications of allogeneic transfusions, like storage lesions and immunologic reactions

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Multiple Choice Questions on this study

In Kalmukov 2022 et al., on cell salvage efficacy, what was the main advantage of swab washing during intraoperative blood salvage?

A. It reduced procedure time
B. It reduced cost
C. It avoided use of anticoagulants
D. It improved RBC concentration
E. It served as an adjunct when direct suction was limited

Answer: It served as an adjunct when direct suction was limited

Explanation: Swab washing is useful when blood accumulates on swabs rather than in cavities, e.g., in soft tissue surgery.
In Kalmukov 2022 et al., on cell salvage efficacy, what was a noted potential **benefit** of cell salvage over allogeneic transfusion in dogs?

A. Increased platelet count
B. Reduced infection risk
C. Eliminated need for surgical suction
D. Removal of leukocytes, reducing cytokine-mediated effects
E. Enhanced storage of erythrocytes

Answer: Removal of leukocytes, reducing cytokine-mediated effects

Explanation: Cell salvage removes leukocytes, potentially reducing transfusion reactions.
In Kalmukov 2022 et al., on cell salvage efficacy, what was the average red blood cell mass (rbcM) recovery percentage?

A. 72.5%
B. 78.0%
C. 84.7%
D. 89.1%
E. 92.0%

Answer: 84.7%

Explanation: Swab washing recovered an average of 84.74% of rbcM.
In Kalmukov 2022 et al., on cell salvage efficacy, what was the mean percentage of red blood cell mass (rbcM) recovered using direct suction?

A. 74.1%
B. 80.2%
C. 84.7%
D. 88.4%
E. 91.2%

Answer: 88.4%

Explanation: Direct suction recovered a mean of 88.43% of the red blood cell mass.
In Kalmukov 2022 et al., on cell salvage efficacy, which statement is TRUE regarding post-salvage PCV values?

A. Suction had significantly higher PCV.
B. Swab washing had significantly higher PCV.
C. PCV was equal pre- and post-salvage.
D. There was no significant difference in post-salvage PCV between methods.
E. Suction had lower PCV than swab washing.

Answer: There was no significant difference in post-salvage PCV between methods.

Explanation: PCV values post-salvage were similar (~34%) between suction and swab washing (p = .220).

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