🔍 Key Findings

• Portal pressure increased proportionally with insufflation pressure: 38% at 6 mmHg, 95% at 10 mmHg, and 175% at 14 mmHg.
• Exponential model: average increase of 7.45% per mmHg of insufflation pressure (CI: 4.7–10.2%).
• No systemic hemodynamic adverse effects were observed; MAP remained >60 mmHg throughout.
• Portal hypertension threshold (15 mmHg) predicted at ~6.4 mmHg insufflation pressure.
• No statistical impact from patient weight, pressure-to-weight ratio, or order of insufflation rounds.
• Measurement technique was feasible and safe, with only minor challenges (e.g., catheter kinking).
• The study supports use of the lowest insufflation pressure needed for visualization to avoid portal hypertension.
• Baseline portal pressures returned after desufflation, supporting comparison pre- and post-attenuation.

🔍 Key Findings Summary

• 95 TPLO procedures reviewed retrospectively with follow-up radiographs
• Rock-back defined as increase in tibial plateau angle (TPA) ≥2° from immediate post-op to recheck
• 21% of stifles (20/95) experienced rock-back
• Mean ΔTPA among rock-back cases = 3.2° ± 2.6°
• No implant failures or tibial tuberosity fractures were reported in these cases
• Plate inclination and exit cut angle (ECA) were not associated with increased risk of rock-back (p = 0.4 and 0.2)
• Authors hypothesize that compression across osteotomy in vivo may mitigate torsional effects from ECA, unlike in gap-model studies
• Emphasizes that rock-back is relatively common, even with well-placed implants

🔍 Key Findings

• PCCLm resulted in significantly fewer postoperative lower urinary tract signs compared to OC (13.0% vs 60.9%, p <.001).
• Incomplete urolith removal was not significantly different between PCCLm and OC (11.4% vs 20%, p = .112).
• PCCLm had significantly shorter anesthesia times than OC when no concurrent procedures were performed (97.5 vs 120 min, p < .001).
• Surgical site infection/inflammation (SSII) rates were low and not significantly different between groups (4.5% PCCLm vs 1.8% OC).
• Dogs undergoing PCCLm were more frequently discharged same-day (84.7% vs 0% in OC), reflecting faster recovery.
• PCCLm had higher intraoperative complication rates (22.1% vs 3.4%), mostly due to incision extension or conversions.
• Time to additional surgery for urolith recurrence was longer in PCCLm dogs (24 vs 11.5 months, p = .004).
• Calcium oxalate uroliths were more prevalent in PCCLm cases, while OC had more struvite or mixed types.

🔍 Key Findings

• Major complications occurred in 25.6% of limbs treated with PAUL, including non-union, implant failure, and infection requiring revision surgery.
• Increased body weight was significantly associated with a higher risk of complications (7% increased risk per additional kg; p = .04).
• Post-operative radiographic assessment was unreliable in predicting complications; inter-observer agreement was poor (kappa ≤ 0.12).
• Expert evaluation of implant or reduction errors had low predictive value (k < 0.2) for postoperative complications.
• Common major complications included non-union (6 limbs), screw breakage, and surgical site infections.
• Implant removal was required in 11.5% of limbs, mostly due to non-union or infection.
• Being a Labrador appeared protective on univariate analysis, but not on multivariate analysis after adjusting for weight.
• Radiographs showing suboptimal plate placement or osteotomy reduction did not reliably correlate with actual complication occurrence.

🔍 Key Findings

Objective: Determine if topical 45 mg/mL amikacin in CMC gel leads to systemic absorption in dogs with wounds.

Dogs enrolled: 11 client-owned dogs, with 31 applications of the gel.

Serum findings:

• Only 5 of 153 samples were above the 2.5 µg/mL quantification limit
• All values remained <5 µg/mL, the presumed toxicity threshold
• No correlation was found between dose-related parameters (mg, mg/kg, mg/cm²) and serum amikacin levels

Peak concentrations were observed at ~2 hours post-application, declining rapidly thereafter

No nephrotoxicity observed, and most values were below detection

Conclusion: Topical amikacin gel appears safe at doses up to 24.9 mg/kg, with minimal systemic absorption

🔍 Key Findings

• Transecting the CCL remnant during TPLO did not reduce patellar ligament thickening (PLT) at any measured point (proximal, mid, distal).
• Transection also failed to reduce postoperative patellar ligament shortening (PLL) at 6 weeks.
• Both groups (transected vs non-transected) showed significant thickening and shortening, with greatest PLT increase at the midpoint.
• Increased PLT was positively correlated with tibial plateau rotation (p = 0.02) and postoperative TPA (p = 0.04).
• No correlation between TT-O (tibial tuberosity width index) and PLT, suggesting narrow osteotomies did not influence PLT in this population.
• Partial CCL rupture was not significantly protective; dogs with partial tears still developed ligament thickening.
• Post-TPLO mid-patellar ligament thickening may relate to Gelpi retractor placement and osteotomy mechanics rather than CCL status.
• Authors do not recommend CCL transection during TPLO to prevent desmitis, citing possible increased instability and degeneration.

🔍 Key Findings

• Lateral approach to ALN extirpation was successful in 100% of cases (44 dogs, 48 ALNs) with consistent anatomical landmarks (costochondral junction of rib 1 and caudal scapular edge).
• Median time for ALN removal was 16.6 minutes, highlighting a fast and efficient dissection method.
• No intraoperative complications were recorded (e.g., hemorrhage or inability to find the lymph node).
• Postoperative complications occurred in 18% of cases, including seromas (n=2), wound dehiscence (n=4), lameness (n=1), and discomfort (n=1).
• Histopathology revealed 56% of ALNs had tumor-related pathology, including overt metastases, early metastasis (HN2), or premetastatic changes (HN1).
• Normal-sized ALNs (<2 cm) still harbored metastases in 22% of cases, emphasizing the unreliability of size as a staging criterion.
• False negatives in cytology occurred in 4 cases, underlining the limitations of cytologic evaluation for staging.
• The technique was reproducible without specialized tools, suggesting wide applicability in general and referral practice.

🔍 Key Findings

• Histologic agreement between 3 mm and 5 mm biopsies was 90%, with a Gwet's AC1 of 0.81 (p < .0001).
• 5 mm biopsies yielded significantly more portal triads and lobules than 3 mm samples (p = .0003 and p < .0001).
• Crush artifacts were significantly higher in 3 mm samples (p = .035), though fragmentation scores were similar (p = .935).
• Both forceps produced adequate samples for histopathology, copper quantification, and bacterial culture.
• No hemorrhage requiring intervention occurred, and both sizes were deemed safe and minimally invasive.
• Surface area ≥40 mm² strongly predicted ≥11 portal triads, a desirable threshold for reliable histopathology.
• Use of 3 mm instruments was easier in small dogs (<12 kg), but more challenging in larger dogs due to shaft length.
• Clinical diagnoses were unaffected by forceps size, even in the one discordant histologic pair.

🔍 Key Findings

• Study Design: Cadaveric model using four large-breed dogs with 10x10 cm full-thickness wounds at four locations (shoulder, thorax, flank, thigh).
• Configurations Tested: Diagonal, opposite, parallel, and perpendicular placements of wound infusion catheter and JP drain.
• Fluid Retrieval:
  • No significant difference by configuration (p = .92) or location (p = .32).
  • Perpendicular configuration had the highest mean retrieval (11.35 mL, 56.8% of instilled volume).
  • Flank location had the lowest retrieval (7.2 mL, 35.9%).
• Surface Area Coverage:
  • Parallel configuration achieved the highest SA coverage (83.4% ± 11.6%, p < .01).
  • Perpendicular was lowest.
• Leakage:
  • No difference in leakage between configurations (p = .74) or locations (p = .10).
  • Leakage commonly occurred at drain or catheter entry points (93.8% of wounds).
• Conclusion: Parallel drain configuration optimized fluid dispersion. Infusion-retrieval systems may allow for topical therapy delivery in closed wounds.

🔍 Key Findings Summary

• IMN provides relative stability, resists bending/torsion due to central axis alignment
• Larger diameter nails = exponentially greater stiffness (∝ D⁴)
• Trade-off: Larger interlocking holes weaken fatigue strength of the nail
• Reaming increases contact/stability but has pros/cons:
  • Improves outcomes in closed fractures
  • May reduce endosteal blood flow in thin-walled bones (e.g., cats)
• Design advances:
  • Angle-stable IMN reduce rotational slack
  • Expandable nails simplify insertion but may compromise removal or compressive load resistance
  • Precontoured nails match bone curvature but lack consistent clinical superiority
• Material debates continue (e.g., titanium vs. stainless steel vs. magnesium)