In Billas 2022 et al., on SSI risk after limb amputation, which variable was **not** associated with increased SSI risk?
A. Use of bipolar sealing device
B. Other-than-clean wound classification
C. Use of sharp dissection
D. Amputation due to infection
E. Amputation due to trauma
Answer: Use of sharp dissection
Explanation: Only bipolar sealing device, trauma, infection, and non-clean wounds were significant predictors.
In Billas 2022 et al., on SSI risk after limb amputation, what was concluded regarding use of electrosurgery for muscle transection?
A. It significantly increased SSI risk
B. It had no association with SSI
C. It significantly decreased SSI risk
D. It was associated with longer surgeries
E. It reduced thermal spread
Answer: It had no association with SSI
Explanation: Monopolar electrosurgery was not associated with increased SSI risk (*P* > .05).
In Billas 2022 et al., on SSI risk after limb amputation, what was the SSI incidence following clean limb amputation procedures?
A. 2.5%
B. 5.2%
C. 8.0%
D. 10.9%
E. 14.3%
Answer: 10.9%
Explanation: SSI occurred in 10.9% of clean amputations, higher than expected for clean surgeries.
In Billas 2022 et al., on SSI risk after limb amputation, which muscle transection method was associated with increased infection odds?
A. Sharp scalpel transection
B. Monopolar electrosurgery
C. Bipolar vessel sealing device
D. Ligature with non-absorbable suture
E. Blunt dissection
Answer: Bipolar vessel sealing device
Explanation: Use of bipolar vessel sealing devices significantly increased the odds of SSI (OR 2.5; *P* = .023).
In Billas 2022 et al., on SSI risk after limb amputation, which amputation indication significantly increased SSI odds compared to neoplasia?
A. Neurologic disease
B. Implant failure
C. Trauma
D. Primary osteosarcoma
E. Other neoplasia
Answer: Trauma
Explanation: Trauma had a 4.5x increased SSI risk compared to neoplasia (*P* = .003).