🔍 Key Findings Summary

• Finite element analysis compared intact radii vs. locking plates placed 1 mm or 3 mm above the bone
• LP placement significantly reduced tensile (maximum principal) stress on cranial cortex, potentially causing implant-induced osteoporosis
• Shell element findings:
  • Max principal stress significantly lower in both LP groups vs. intact (p < 0.05)
• Solid element findings:
  • Equivalent stress higher and max principal stress lower in LP groups
• Implication: Tension reduction may impair bone remodeling; implant design and placement height affect stress environment

🔍 Key Findings

• Both patient-specific and universal guides yielded correction errors <2°, with no statistically significant difference in accuracy.
• Universal guide corrected aLDFA up to 24° and AA up to 20°, addressing multiplanar deformities effectively.
• Patient-specific guides allowed for preoperative simulation, providing more stable pin placement and potentially aiding less-experienced surgeons.
• Universal guide eliminated the need for CT-based customization, reducing time and cost.
• Cadaver and bone model trials showed consistent accuracy, validating both methods in vitro and ex vivo.
• No significant differences in outcome when correcting uniplanar (aLDFA) vs biplanar (aLDFA + AA) deformities.
• Universal guide's fixed size presented limitations in small dogs, potentially requiring multiple size options.
• Universal guide showed potential for standard use, offering repeatable outcomes with minimal prep despite needing precise intraoperative placement.

🔍 Key Findings Summary

• No significant difference in mechanical properties between contoured vs non-contoured SOP-LC rods
• Clamp configuration significantly influenced mechanical performance:
  • Single-side clamps → ↑ yield load, ↑ displacement, ↑ bending strength (p < 0.05)
  • Alternating-side clamps → ↑ initial torsional stiffness (p = 0.029)
• Clamp slippage was evident only in torsional tests; screw loosening may be torque-dependent
• Mild screw bending and construct offset suggest subtle instability
• Recommends clamp configuration choice based on loading scenario
• Suggests 3.0 Nm torque may be more effective than 2.5 Nm to prevent clamp slippage

🔍 Key Findings

• 12-hole LCPs (80% plate–bone ratio) showed significantly higher construct stiffness than 6-, 8-, or 10-hole plates in both compression and tension bending.
• Strain on the plate was significantly lower in 12-hole vs 6-hole plates at all regions of interest (ROIs), especially around the fracture gap.
• No incremental increases in stiffness or decreases in strain were observed between 6-, 8-, and 10-hole plates—only when comparing to 12-hole plates.
• Bone model strain adjacent to the plate end was significantly lower for 10- and 12-hole plates vs 6-hole plates under both loading conditions.
• The threshold effect suggests biomechanical benefits only emerge beyond a plate–bone ratio of ~80%.
• Working length increased from 9.4 mm (6-hole) to 13 mm (others), potentially influencing strain/stiffness differences.
• Four-point bending was used, as it replicates the most biomechanically relevant force on plated long bones.
• Clinical implication: Longer plates may reduce plate strain and peri-implant bone strain, potentially lowering risk of fatigue failure or stress risers.

🔍 Key Findings

• Short working length constructs had significantly higher stiffness and lower strain than long constructs in compression bending (p = 0.0172).
• In tension bending, short constructs also had higher precontact stiffness and lower strain, but this reversed after transcortical contact (~150 N).
• Transcortical contact increased stiffness only in long constructs, producing a bilinear load-displacement curve.
• Postcontact stiffness was higher in long constructs, but this may not reflect clinical benefit due to risks of high interfragmentary strain.
• Short working length reduced strain at multiple ROIs under both loading conditions, including over fracture gap (Tables 1–3).
• Increased working length promoted stress concentration and deformation, especially in compression bending.
• In vitro benefits of long constructs (via contact stability) may not translate to healing, as repetitive loading could increase plate strain and bone resorption.
• Plate strain was effectively mapped using 3D digital image correlation, confirming regional strain differences between configurations.

🔍 Key Findings

• LVSG was successfully performed in 9/10 cadavers and both live cats, demonstrating procedural feasibility.
• Mean stomach resected was 27.6% of total weight in cadavers, with no leaks in 8/8 tested or either live patient.
• Mean surgical time: 110.4 min (cadavers) and 115 min (live cats); no intra- or postoperative complications observed.
• Stenosis near the incisura occurred in 2 cadavers; attributed to staple placement too close to the lesser curvature.
• 3D printed cannulas (3DPCs) improved ergonomics and were used in 6/10 cadavers and both live procedures.
• Live cats lost 21–24% body weight over 3 months, with full return to pre-surgical BCS and no GI complications.
• Orogastric tube and proper tensioning were critical in preventing gastric stenosis during staple placement.
• No reinforcement or oversew was used on the staple line; TriStaple cartridges provided reliable closure.

🔍 Key Findings

40 dogs underwent splenectomy using 16 bipolar vessel sealing devices (VSDs)
Devices were reused up to 4 times after handwashing and ethylene oxide (EtO) sterilization
Biologic debris was found in 100% of devices, specifically under the transection blade, even after a single use

• Mostly scant (14/16) or mild (2/16) debris

No devices or debris yielded positive aerobic culture after EtO sterilization
EtO sterilization proved microbiologically effective despite visible residue
Perioperative failure rate: 1 device (malfunctioned during first activation)

🔍 Key Findings

• Short working length constructs had significantly higher stiffness and lower strain than long constructs in compression bending (p = 0.0172).
• In tension bending, short constructs also had higher precontact stiffness and lower strain, but this reversed after transcortical contact (~150 N).
• Transcortical contact increased stiffness only in long constructs, producing a bilinear load-displacement curve.
• Postcontact stiffness was higher in long constructs, but this may not reflect clinical benefit due to risks of high interfragmentary strain.
• Short working length reduced strain at multiple ROIs under both loading conditions, including over fracture gap (Tables 1–3).
• Increased working length promoted stress concentration and deformation, especially in compression bending.
• In vitro benefits of long constructs (via contact stability) may not translate to healing, as repetitive loading could increase plate strain and bone resorption.
• Plate strain was effectively mapped using 3D digital image correlation, confirming regional strain differences between configurations.

🔍 Key Findings Summary

• Subjects: 11 animals (8 dogs, 3 cats)
• Technique: Uncovered balloon-expandable metallic biliary stents (BEMBS)
• Indications: Cholelithiasis, strictures, neoplasia, cholangiohepatitis, etc.
• Success: Patency achieved in all animals surviving to discharge
• Complications:
  • Short-term mortality: 2/11 (1 euthanized for SIRS, 1 unknown)
  • Long-term issues: cholangiohepatitis, choledocholithiasis, stent occlusion (in cats only)
• Long-term patency:
  • Dogs: median 650.5 days
  • Cats: median 446 days
• Stent removal possible even after >600 days in some cats
• Clinical outcome: Viable alternative to plastic stents or cholecystoenterostomy

🔍 Key Findings

• LVSG was feasible in 9/10 feline cadavers with successful stapled gastrectomy and minimal technical complications.
• Stenosis at the incisura angularis occurred in 2/10 cadavers, associated with staple placement too close to the lesser curvature.
• Leak testing was negative in 8 cadavers and both live cats, indicating effective staple sealing.
• Mean stomach resection was ~28%, though less than human standards (~75–80%) for metabolic effects.
• Surgery was performed safely in two live feline subjects, with no intraoperative or postoperative complications over a 6-month follow-up.
• Technique refinements included orogastric tube placement and custom 3D-printed cannulas to improve staple line accuracy and avoid stenosis.
• Tri-Staple purple cartridges provided graduated compression suited for feline gastric tissue thickness (~2.5 mm).
• No need for staple line oversew in live cats; staple-only closure proved safe in this short-term study.