🔍 Key Findings

• Histologic agreement between 3 mm and 5 mm biopsies was 90%, with a Gwet's AC1 of 0.81 (p < .0001).
• 5 mm biopsies yielded significantly more portal triads and lobules than 3 mm samples (p = .0003 and p < .0001).
• Crush artifacts were significantly higher in 3 mm samples (p = .035), though fragmentation scores were similar (p = .935).
• Both forceps produced adequate samples for histopathology, copper quantification, and bacterial culture.
• No hemorrhage requiring intervention occurred, and both sizes were deemed safe and minimally invasive.
• Surface area ≥40 mm² strongly predicted ≥11 portal triads, a desirable threshold for reliable histopathology.
• Use of 3 mm instruments was easier in small dogs (<12 kg), but more challenging in larger dogs due to shaft length.
• Clinical diagnoses were unaffected by forceps size, even in the one discordant histologic pair.

🔍 Key Findings Summary

• Finite element analysis compared intact radii vs. locking plates placed 1 mm or 3 mm above the bone
• LP placement significantly reduced tensile (maximum principal) stress on cranial cortex, potentially causing implant-induced osteoporosis
• Shell element findings:
  • Max principal stress significantly lower in both LP groups vs. intact (p < 0.05)
• Solid element findings:
  • Equivalent stress higher and max principal stress lower in LP groups
• Implication: Tension reduction may impair bone remodeling; implant design and placement height affect stress environment

🔍 Key Findings

• CBLO fixation with both a headless compression screw (HCS) and tension band (TB) showed the highest yield and ultimate loads compared to other configurations
• HCSTB constructs had significantly higher yield load (1212 N) and ultimate load (1388 N) than Plate alone (788 N, 774 N), HCS alone (907 N, 927 N), or TB alone (1016 N, 1076 N)
• No difference in construct stiffness was detected among the four fixation methods tested
• All constructs ultimately failed by bone fracture—location of failure differed by construct type (e.g., through HCS hole or cranial screw hole)
• TB and HCSTB groups showed failure via progressive TB stretching and cranial osteotomy widening, while Plate and HCS failed more abruptly
• All constructs withstood forces exceeding expected quadriceps load in vivo (170–325 N), suggesting all methods can resist physiological loading, but HCSTB provides greater safety margin
• HCS alone was not significantly stronger than Plate or TB alone, questioning its standalone superiority
• Study supports using TB and HCS together for optimal construct strength, but clinical studies are needed to validate implant fatigue, healing, and failure rates

🔍 Key Findings Summary

• 48 dogs (60 stifles) underwent custom 3D-printed TRP implantation for patellar luxation
• 24 treated with TRP alone; 36 with additional procedures (e.g., DFO, TTT)
• Success rate: 59/60 corrected patellar tracking
• Functional outcome: 57/60 full function, 2 acceptable, 1 unacceptable
• Complication rate: 3 total (2 minor, 1 major recurrence)
• TRP spares cartilage unlike trochleoplasty, offering implant-based ridge augmentation
• No implant loosening or infection observed

🔍 Key Findings

Design: Ex vivo cadaver study (n=8 dogs, 24 sites)
Comparison: Freehand vs. 3D-printed drill guide-assisted ventral slot (GAVS vs FHVS)
Findings:

• GAVS produced slots not significantly different from planned dimensions (p = .722–.875)
• FHVS produced significantly shorter slots than intended (p < .01)
• No difference in surgical time (p = .071)
• Shape ratio and slot divergence from midline were similar between groups (p > .4)
• Use of guide significantly reduced variability in slot position (63% → 29%), shape (65% → 24%), and divergence (54% → 50%)

Conclusion: 3D-printed guides improved accuracy and consistency of ventral slot creation by novice surgeons; supports future evaluation in live dogs and small breeds

🔍 Key Findings

• NIRF altered surgical strategy in 3 of 20 GDV dogs, identifying necrosis not appreciated subjectively.
• Fundic fluorescence <10% indicated histologically confirmed gastric necrosis.
• In 1 dog, NIRF revealed nonviability despite the surgeon’s impression of viability.
• Staple line fluorescence resembled viable tissue in the only stapled gastrectomy, suggesting preservation of perfusion.
• GDV dogs (even “viable”) showed lower fluorescence vs. healthy controls, indicating subclinical vascular compromise.
• Histology confirmed full-thickness necrosis in all 4 dogs with NIRF-defined nonviability.
• Pre-op lactate was significantly higher in nonviable GDV dogs (8.55 vs 4.89 mmol/L, p=0.03).
• No complications were reported from ICG use; imaging was safe and repeatable.

🔍 Key Findings

Study size: 105 dogs (73 ORPS; 32 MIPO)

MIPO vs ORPS differences:

• Surgical time: MIPO median 130 min vs ORPS 85 min (p < .001)
• Explant rate: MIPO 25% vs ORPS 4.1% (p = .003)
• Time to clinical union: MIPO 85 days vs ORPS 57 days (p = .010)
• Frontal alignment deviation: MIPO 3.5° vs ORPS 2.0° (p = .047)
• Comminution more frequent in MIPO (41% vs 16%; p = .012)

Significant predictors for MIPO use: More proximal fracture margin (p = .004), surgeon identity (p < .001)

No significant difference: Sagittal alignment, radial length, union rate, or complication rate by surgeon

Implant preference: Fixin plates used in 84% of MIPO; locking plates more common in ORPS

🔍 Key Findings

Sample: 373 cats with high-rise syndrome (HRS) from 2017–2020.
ATTS was the only significant predictor of survival (p < 0.001); each point increase decreased survival odds (OR = 0.46).
AUC for ATTS ROC curve: 0.857 (95% CI: 0.788–0.926).
Floor height, lesion type, and ground surface were not significantly associated with survival.
Odds of injury were 7.98× higher when landing on hard vs. soft surface (p < 0.001).
16.96× increased injury risk from the fourth vs. third floor (p = 0.008).
Cats with ATTS ≥7 had 62% mortality; median ATTS increased with floor height (r = 0.244, p < 0.001).
Thoracic and vertebral trauma were most common causes of death.
Only 32% of cats had the “classic” HRS triad (pneumothorax, epistaxis, hard palate fracture).

🔍 Key Findings

• Liposomal bupivacaine (LB) infiltration did not reduce the need for rescue analgesia compared with placebo in dogs undergoing TPLO.
• CMPS-SF pain scores were not significantly different between LB and placebo groups at any postoperative time point.
• % body weight distribution (%BWdist) to the operated limb did not differ significantly between treatment groups across all time points.
• No correlation was found between CMPS-SF scores and %BWdist, suggesting these metrics assess different aspects of postoperative pain.
• Postoperative carprofen administration was standardized, and LB did not provide additional detectable analgesic benefit.
• Three-layer infiltration technique (joint capsule, fascia, subcutis) was used consistently across all cases.
• Adverse events were minor and comparable between LB and placebo groups.
• Post hoc analysis suggested a much larger sample size (58–436 dogs) would be needed to detect significant differences in %BWdist.

🔍 Key Findings Summary

• Evaluated ideal dorsolateral implant trajectories in T1–T13 using CT in 30 dogs across five weight classes.
• Corridor widths were narrowest in the mid-thoracic vertebrae (as little as 1.8 mm) and increased cranially and caudally.
• Allowable deviation angles (ADA) were often very small (as little as 3°), indicating high risk for canal or thoracic structure breach.
• Distances to critical structures (lungs, aorta, subclavian artery, azygos vein) were often <1 mm, even in large dogs.
• Data suggest extreme caution and precision are needed for thoracic vertebral implant placement and support use of navigation or 3D-printed guides.