🔍 Key Findings

Subject: 7-year-old Labrador underwent cementless total knee replacement (TKR) due to severe stifle OA.

Clinical function:

• Improved ROM from 90° pre-op to 120° post-op.
• Weight-bearing increased from toe-touching to 70% bodyweight by 6 weeks post-op.
• No visible lameness by 14 weeks.

Implant performance:

• No complications at any follow-up points.
• No osteolysis, loosening, or metallosis at 6-year necropsy.

Wear evaluation:

• Mild UHMWPE insert wear, localized to caudal edges.

Histologic findings:

• Robust osseointegration at implant-bone interface.
• Fibrous tissue only in areas lacking porous coating.

Conclusion:

• Cementless TKR demonstrated excellent 6-year survival and functional outcomes.
• Support for considering early surgical intervention in severe stifle OA.

🔍 Key Findings

• Microvascular density at the site of foreign body obstruction was significantly lower in obstructed dogs compared to healthy controls.
• PBR (perfused boundary region) was paradoxically lower in obstructed dogs, indicating that PBR may not reliably correlate with tissue viability in this context.
• No significant difference in microvascular perfusion between subjectively viable vs nonviable intestines, suggesting subjective assessment is unreliable.
• No difference in perfusion parameters between handsewn and stapled enterectomies, indicating both techniques preserve vascular health equally.
• Stapled enterectomy using green TA staples is safe and did not impair intestinal perfusion at the anastomosis site.
• SDF videomicroscopy is feasible intraoperatively and can differentiate healthy from diseased intestine in dogs.
• Surgeons' subjective evaluations led to potentially unnecessary enterectomies, as microvascular parameters did not differ.
• No cases of dehiscence or mortality, suggesting both surgical approaches are effective when applied properly.

🔍 Key Findings

• Objective: Evaluate feasibility and accuracy of 3D-printed patient-specific drill guides for iliosacral screw placement in cadaver dogs.
• N = 10 canine cadavers (20 hemipelves); screw placement done using fluoroscopic-assisted patient-specific guides (PSG).
• Median cortical breach grade: 0 (IQR 0–1) for all screws.
  19/20 screws breached sacral canal wall (all ≤ grade 2), but no screws breached canal contents (grade 3).
• Median trajectory deviation: 0.88° transverse, 0.72° dorsal.
• Procedure time: Median 7.2 minutes for guide placement and drilling.
• Conclusions: PSG-assisted screw placement was safe, accurate, and fast, offering clinical potential in pelvic trauma.

🔍 Key Findings

• Bacterial fluorescence was detected in all wounds (17 dogs, 4 cats) using the point-of-care wound imaging device (WID).
• The WID confirmed the presence of clinically relevant wound infection in all evaluated cases at the time of imaging.
• No significant difference was found in bacterial yield or burden between image-guided and non-guided swabs (QBC and PCR; p > 0.05).
• The WID helped guide wound debridement in some cases by localizing areas of fluorescence, especially in necrotic tissue.
• Most infections were polymicrobial and dominated by anaerobes, highlighting the need for anaerobic culture inclusion.
• PCR analysis showed low bacterial DNA yields, often complicated by host DNA contamination, limiting its utility.
• The study did not evaluate sensitivity/specificity of WID, as only fluorescence-positive wounds were included.
• Clinical utility of WID lies in immediate visual confirmation of infection, supporting timely antimicrobial treatment decisions.

🔍 Key Findings

• Telovelar approach enabled complete resection of a fourth ventricle choroid plexus tumor in a dog without postoperative complications.
• Postoperative MRI confirmed gross total tumor removal, and the dog remained neurologically normal 28 months post-surgery.
• The tela choroidea was used as a surgical landmark and incised to allow atraumatic access to the tumor.
• Cerebellum was spared using this technique, minimizing risk of cerebellar injury (e.g., cerebellar mutism).
• No hemorrhagic complications were noted during surgery due to dissection through avascular planes.
• Histopathology favored choroid plexus carcinoma based on mitotic index (9/10 HPFs), though definitive diagnosis remained pending.
• The case highlights the utility of telovelar over transvermian approach, given its minimally traumatic nature and improved exposure.
• Survival beyond 2 years without adjunctive therapy suggests surgical excision alone may be curative in select cases.

🔍 Key Findings

• Fewer R1 margins (tumor on ink) were achieved in mast cell tumors (MCTs) when using 6–10 mm lateral margins versus 0–5 mm (7% vs. 55%; _P_ = .049).
• For soft tissue sarcomas (STSs), no benefit was seen in margin completeness between 0–5 mm vs. 6–10 mm lateral margins (41% vs. 43% R1).
• Overall R1 rates were 26% for MCTs and 42% for STSs following PNE.
• R scheme (“tumor on ink” = R1) had better interobserver agreement (83%) compared to ≤1 mm margin criteria (68% agreement).
• Complication rate was moderate (26%), but no surgeries required revision.
• Local recurrence/metastasis occurred in 14% of dogs, with 60% of those having R1 margins.
• Adjunctive therapy was considered clinically indicated in 46% of 0–5 mm margin cases vs. 24% of 6–10 mm cases.
• Histologic grade and tumor size were not predictive of margin completeness.

🔍 Key Findings

• Aiming device provided comparable trajectory accuracy to fluoroscopy, especially in right limbs (1.9° vs. 3.4°, p = .0128).
• Eccentricity (deviation from condylar center) was lower with fluoroscopy (3.1 mm vs 4.2 mm, p = .0017), making fluoroscopy more precise.
• Odds of joint infringement were 8× higher with the aiming device, though not statistically significant (p = .0575).
• Residents had greater screw trajectory deviation than diplomates (p = .0366), highlighting impact of experience.
• Aiming device procedures took less time than fluoroscopy in some scenarios, particularly for right limbs with right-handed surgeons.
• Fluoroscopic procedures had more pin/drill attempts, increasing risk of glove puncture and potential aseptic breaks.
• Mean deviation angles in both groups (<3.5°) were within acceptable range to avoid intracondylar fracture gap.
• Cadaver model used large-breed, healthy adult dogs, not small-breed immature dogs, limiting generalizability.

🔍 Key Findings

The study included 162 deep-pain-negative dogs undergoing decompressive surgery (hemilaminectomy) for acute thoracolumbar intervertebral disc extrusion (IVDE).

Ambulatory recovery occurred in 53.1% of dogs (86/162).

The best performing machine-learning model was XGBoost, with an AUC of 0.9502 and accuracy of 89.1%, outperforming Ridge, AdaBoost, and Naive Bayes models.

Preoperative-only XGBoost models were less accurate, with AUC dropping to 0.8271 and accuracy to 71.9%.

Top predictive features (by SHAP analysis) included:

1. T2-weighted to L2 spinal cord signal ratio (lower values predicted better outcome)
2. Use of fenestration (presence associated with better recovery)
3. Hospitalization duration
4. Imaging modality used
5. Duration of nonambulatory status

Machine learning provided better insight into prognostic factors than traditional statistical methods.

🔍 Key Findings

• Cholelithiasis was the most common indication for cholecystectomy in cats.
• Perioperative complications were frequent, with intraoperative hypotension in all recorded cases and postoperative anemia in 14 cats.
• Perioperative mortality was 21.7%, lower than historical rates for feline biliary surgery.
• 78.3% of cats survived to discharge, and 83.3% of those lived >6 months; 44.4% survived >3 years.
• Vomiting was the most common short- and long-term complication, though most cats were medically managed.
• Concurrent EHBDO was not a contraindication provided CBD patency was restored.
• Positive bacterial cultures were found in 15 cats, with E. coli and Enterococcus faecalis most common.
• Owner-reported outcomes were excellent in all cats that survived long-term.

🔍 Key Findings

• CBLO fixation with both a headless compression screw (HCS) and tension band (TB) showed the highest yield and ultimate loads compared to other configurations
• HCSTB constructs had significantly higher yield load (1212 N) and ultimate load (1388 N) than Plate alone (788 N, 774 N), HCS alone (907 N, 927 N), or TB alone (1016 N, 1076 N)
• No difference in construct stiffness was detected among the four fixation methods tested
• All constructs ultimately failed by bone fracture—location of failure differed by construct type (e.g., through HCS hole or cranial screw hole)
• TB and HCSTB groups showed failure via progressive TB stretching and cranial osteotomy widening, while Plate and HCS failed more abruptly
• All constructs withstood forces exceeding expected quadriceps load in vivo (170–325 N), suggesting all methods can resist physiological loading, but HCSTB provides greater safety margin
• HCS alone was not significantly stronger than Plate or TB alone, questioning its standalone superiority
• Study supports using TB and HCS together for optimal construct strength, but clinical studies are needed to validate implant fatigue, healing, and failure rates