Williams et al: Evaluation of the addition of adrenaline in a bilateral maxillary nerve block to reduce hemorrhage in dogs undergoing sharp staphylectomy for brachycephalic obstructive airway syndrome. A prospective, randomized study
Veterinary Surgery 1, 2024

🔍 Key Findings Summary

• Design: Prospective, randomized, double-blinded controlled trial
• Population: 32 brachycephalic dogs undergoing cut-and-sew sharp staphylectomy
• Groups: Adrenaline + lidocaine (Group A) vs. Lidocaine only (Group NA)
• Main Findings:
  • Total hemorrhage significantly lower in Group A (median 1.82 g) vs Group NA (7.95 g); p = .013
  • Normalized hemorrhage significantly lower in Group A; p = .021
  • Surgeon-assigned hemorrhage scores significantly lower in Group A; p = .029
  • No adverse effects (tachycardia, hypertension, arrhythmia, etc.) noted from adrenaline use
  • Breed effect: English Bulldogs bled more overall even after normalization
• Clinical Implication: Adrenaline in nerve blocks reduces hemorrhage without added risk