Carvajal et al: Serum acute-phase protein concentrations following uncomplicated total hip arthroplasty in dogs
Veterinary Surgery 1, 2023

🔍 Key Findings

  • C-reactive protein (CRP) and serum amyloid A (SAA) levels remained low at 3 and 6 months after uncomplicated THA in dogs.
  • No significant differences were observed in CRP or SAA between preoperative, 3-month, and 6-month time points.
  • Mean CRP values were 3.8 mg/L pre-op, 0.8 mg/L at 3 months, and 1.4 mg/L at 6 months.
  • Mean SAA values were 13.9 mg/L pre-op, 14.1 mg/L at 3 months, and 18.4 mg/L at 6 months.
  • All dogs recovered normally with no complications or persistent signs of inflammation at follow-up.
  • Study establishes baseline CRP and SAA levels for dogs post-THA, useful for comparison in suspected PJI.
  • These markers may help differentiate periprosthetic joint infection (PJI) if values deviate from baseline post-THA.
  • NSAID therapy was discontinued by 6 months in all dogs, possibly reflecting decreased inflammation.

Simini Surgery Review Podcast

How critical is this paper for crushing the Boards?

🚨 Must-know. I’d bet on seeing this.

📚 Useful background, not must-know.

💤 Skip it. Doubt it’ll ever show up.

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