🔍 Key Findings

• Electroceutical dressing (PED) promoted complete healing of chronic wounds in both a dog and a cat previously unresponsive to standard therapies.
• Infection clearance occurred in both animals by the end of PED therapy, as shown by negative culture results.
• In the dog, wound area reduced by ~4.2× over 10 days; healing completed by day 67 with no further antibiotic therapy.
• In the cat, wound area reduced by ~2.5× over 17 days; healing completed by day 47 without systemic antibiotics.
• PEDs function via direct current (DC) stimulation, believed to generate hypochlorous acid (HOCl) with antibacterial properties.
• No side effects or adverse tissue reactions were observed in either case, supporting biocompatibility.
• Multidrug-resistant organisms (e.g., S. pseudintermedius, S. canis, S. epidermidis) were eradicated by PED treatment.
• PED therapy may reduce reliance on antibiotics and surgery, offering a novel adjunct for chronic, infected wounds.

🔍 Key Findings

• No infections (0/102) occurred in cases where preclosure povidone-iodine lavage (PrePIL) was used, compared to 21/2111 (0.99%) with saline lavage.
• Break-even cost for PrePIL was calculated at $49.74, while the actual cost was only $2.07, confirming strong cost-effectiveness.
• No adverse reactions or healing complications were reported in the 102 PrePIL cases.
• The PrePIL protocol used 0.35% povidone-iodine for 3 minutes before closure, followed by sterile saline lavage.
• Majority of THRs (97%) used cementless fixation (BFX) in PrePIL group; only 3 cases used CFX components.
• Surgeries followed consistent perioperative antibiotic protocols, making PrePIL the only major protocol variable.
• Antibiotics were not added to lavage, aligning with WHO and CDC guidelines for antimicrobial stewardship.
• The infection reduction with PrePIL supports routine use in total hip replacement to reduce periprosthetic joint infections.

🔍 Key Findings Summary

• Subtotal coronoidectomy improved vertical and propulsive forces, but braking forces remained subnormal at 26 weeks.
• No significant benefit was seen from ACP vs placebo at any timepoint across all force parameters or lameness scores.
• Force plate analysis was more sensitive than visual lameness scoring.
• Braking force (%FY+) was best at detecting persistent lameness, and SI < 0.9 persisted in most dogs at 26 weeks.
• Outcome less favorable than historically reported — challenges status of subtotal coronoidectomy as “gold standard” for MCD.

🔍 Key Findings

• Adding Locking Head Inserts (LHI) to a 3.5-mm LCP had no effect on plate strain, stiffness, or deformation in an open fracture gap model.
• Peak strain consistently occurred at the Combi-hole over the fracture gap, with values up to ~1837 µε.
• No significant difference in strain was found across configurations with 0, 3, or 9 LHI (p = 0.847).
• Construct stiffness and compressive displacement also remained unchanged regardless of LHI count (p = 0.311 and 0.069 respectively).
• Study contradicted the hypothesis that LHI would reduce strain and increase stiffness under biologic loading.
• Combi-hole design may limit the efficacy of LHI, as LHI only fill the locking portion, not the compression side where strain peaks.
• Implant fatigue risk remains highest over unfilled screw holes, especially over fracture sites—confirming previous failure patterns.
• Surgeons should consider alternative methods to reduce strain when facing high implant load scenarios.

🔍 Key Findings

Study type: Cadaveric stifle arthroscopy in large breed dogs (n=12 joints from 6 dogs)
Goal: Describe and assess the proximal lateral portal for insertion of a Ventura stifle thrust lever (VSTL)
Main results:

• No damage to the long digital extensor tendon (LDE) with this portal
• VSTL could be placed without removing the arthroscope
• Portal creation time ~37 seconds (faster than previously reported)

Cartilage impact:

• Superficial iatrogenic articular cartilage injury (IACI) present in all specimens
• No difference in IACI between 5- and 10-minute lever durations
• Zone 4 (lateral femoral condyle) had significantly more damage than zones 1–3 (p < .05)

Conclusion: Portal was safe, repeatable, minimally invasive, and did not increase cartilage damage with up to 10-minute lever use

🔍 Key Findings:

• Design: Ex vivo study with 24 paired limbs from normal beagle dogs.
• Osteotomy types (3 groups):
  1. 30° uniplanar frontal wedge
  2. Oblique (30° frontal, 15° sagittal)
  3. Single oblique (30° frontal, 15° sagittal, 30° external rotation)
• Comparison: 3D PSG vs Freehand (FH)
• Main Outcomes:
  • PSG accuracy: Mean angular deviation = 2.8° vs 6.4° in FH (p < .001).
  • 84% of PSG osteotomies were within 5° of target vs 50% of FH.
• Significant improvements with PSG in:
  • Group 1 (uniplanar frontal) proximal and distal frontal planes (p < .001, .006)
  • Group 3 (SOO) frontal and sagittal planes (p = .002, .043)
• Time: PSG faster in complex SOO group (84s vs 162s, p < .001); no difference in others.
• No difference in osteotomy location (mm) between methods.
• Clinical relevance: PSG more consistent and accurate, especially for complex cuts.

🔍 Key Findings

• Cholelithiasis was the most common indication for cholecystectomy in cats.
• Perioperative complications were frequent, with intraoperative hypotension in all recorded cases and postoperative anemia in 14 cats.
• Perioperative mortality was 21.7%, lower than historical rates for feline biliary surgery.
• 78.3% of cats survived to discharge, and 83.3% of those lived >6 months; 44.4% survived >3 years.
• Vomiting was the most common short- and long-term complication, though most cats were medically managed.
• Concurrent EHBDO was not a contraindication provided CBD patency was restored.
• Positive bacterial cultures were found in 15 cats, with E. coli and Enterococcus faecalis most common.
• Owner-reported outcomes were excellent in all cats that survived long-term.

🔍 Key Findings

• Liposomal bupivacaine (LB) infiltration did not reduce the need for rescue analgesia compared with placebo in dogs undergoing TPLO.
• CMPS-SF pain scores were not significantly different between LB and placebo groups at any postoperative time point.
• % body weight distribution (%BWdist) to the operated limb did not differ significantly between treatment groups across all time points.
• No correlation was found between CMPS-SF scores and %BWdist, suggesting these metrics assess different aspects of postoperative pain.
• Postoperative carprofen administration was standardized, and LB did not provide additional detectable analgesic benefit.
• Three-layer infiltration technique (joint capsule, fascia, subcutis) was used consistently across all cases.
• Adverse events were minor and comparable between LB and placebo groups.
• Post hoc analysis suggested a much larger sample size (58–436 dogs) would be needed to detect significant differences in %BWdist.

🔍 Key Findings

• 3D-printed drill guides (3D-GDT) significantly reduced craniocaudal and dorsoventral drilling angle deviation compared to free-hand drilling technique (FHDT), with statistical significance (p < .0001 and p = .01 respectively).
• No sacral corridor breaches occurred with 3D-GDT, whereas FHDT resulted in 20% drill exit incidences (3/15 cases).
• 3D-GDT had lower deviation from optimal drill trajectory at end points in all axes: craniocaudal (1.84 ± 1.6 mm vs. 4.18 ± 2.4 mm), dorsoventral (1.11 ± 1.0 mm vs. 2.4 ± 1.5 mm), and 3D linear (2.47 ± 1.4 mm vs. 5.35 ± 2.2 mm), all statistically significant.
• Strong correlation (r = 0.77) between CT and 3D software measurements validated method reliability.
• 3D guide trajectories showed consistent proximity to the optimal trajectory, especially at drill endpoints, indicating reduced variability in execution.
• 3D-GDT was developed using open-source software and inexpensive materials, supporting future clinical application.
• Major errors in FHDT occurred primarily at the drill endpoint, underscoring the challenge of maintaining optimal angulation during free-hand drilling.
• The sacral corridor was recharacterized as pyramidal (not quadrilateral), with implications for safer implant placement.

🔍 Key Findings

Subject: 7-year-old Labrador underwent cementless total knee replacement (TKR) due to severe stifle OA.

Clinical function:

• Improved ROM from 90° pre-op to 120° post-op.
• Weight-bearing increased from toe-touching to 70% bodyweight by 6 weeks post-op.
• No visible lameness by 14 weeks.

Implant performance:

• No complications at any follow-up points.
• No osteolysis, loosening, or metallosis at 6-year necropsy.

Wear evaluation:

• Mild UHMWPE insert wear, localized to caudal edges.

Histologic findings:

• Robust osseointegration at implant-bone interface.
• Fibrous tissue only in areas lacking porous coating.

Conclusion:

• Cementless TKR demonstrated excellent 6-year survival and functional outcomes.
• Support for considering early surgical intervention in severe stifle OA.