Parlier et al: Prospective, randomized, clinical trial on the effects of laparoscopic insufflation pressures on portal pressures in dogs
Veterinary Surgery 4, 2024

🔍 Key Findings

• Portal pressure increased proportionally with insufflation pressure: 38% at 6 mmHg, 95% at 10 mmHg, and 175% at 14 mmHg.
• Exponential model: average increase of 7.45% per mmHg of insufflation pressure (CI: 4.7–10.2%).
• No systemic hemodynamic adverse effects were observed; MAP remained >60 mmHg throughout.
• Portal hypertension threshold (15 mmHg) predicted at ~6.4 mmHg insufflation pressure.
• No statistical impact from patient weight, pressure-to-weight ratio, or order of insufflation rounds.
• Measurement technique was feasible and safe, with only minor challenges (e.g., catheter kinking).
• The study supports use of the lowest insufflation pressure needed for visualization to avoid portal hypertension.
• Baseline portal pressures returned after desufflation, supporting comparison pre- and post-attenuation.